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Fig. 6 | BMC Veterinary Research

Fig. 6

From: Establishment of canine mammary gland tumor cell lines harboring PI3K/Akt activation as a therapeutic target

Fig. 6

Activation of the PI3K-Akt signaling pathway in MGT cell lines. (A) GSEA enrichment plots of MGT cell lines. (B) Western blot analysis of phosphorylated-Akt (Ser473), Akt, GAPDH in MGT cell lines. (C) Electropherogram of PIK3CA (H1047R) gene mutation status sequencing. (D) Antiproliferative activity of BYL719 in MGT cell lines and MDCK, TP53 K/O fibroblast. (E) The IC50 values of BYL-719 in MGT cell lines and MDCK, TP53 K/O fibroblast. ***P < 0.001

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BMC Veterinary Research

ISSN: 1746-6148

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