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Table 2 Analgesic effectiveness and dosage rates stratified by MC1R genotype observed in this cohort. Chi-squared p-value = 0.08. Analgesic effectiveness scored one (least effective) to three (most effective)

From: Preliminary investigation of potential links between pigmentation variants and opioid analgesic effectiveness in horses during cerebrospinal fluid centesis

MC1R Genotypes

Mean analgesic effectiveness

Median analgesic effectiveness

Mean dosage rate (mg/kg BW)

Median dosage rate (mg/kg BW)

E/E (n = 11)

2.8

3

0.015

0.017

E/e (n = 20)

2.7

3

0.015

0.016

e/e (n = 18)

2.1

2

0.014

0.01