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Table 2 The effect of letrozole administration (72 µg/kg, PO) on semen quality parameters and sperm kinematics (means ± SD) studied before (day 0), during (day 14 and 28), and after (day 42) treatment of adult mixed breed dogs

From: Effects of short-term oral letrozole on fresh semen parameters, endocrine balance, and prostate gland dimensions in domestic dogs

Factors

Day

Changes (%)

0

14

28

42

Sperm parameters

Live Sperm (%)

88.43 ± 1.57ac

87.43 ± 1.78a

93.00 ± 1.00bc

94.00 ± 0.69b

6.30

Abnormal Morphology (%)

2.29 ± 0.18

3.29 ± 0.52

3.14 ± 0.74

4.86 ± 0.91

112.23

HOST Positive (%)

93.86 ± 2.14

95.00 ± 1.15

91.43 ± 2.84

95.71 ± 0.84

1.97

Sperm Concentration (million/ml)

184.79 ± 45.89a

202.60 ± 27.05a

335.29 ± 30.68b

324.43 ± 37.40b

75.57

Sperm kinematic parameters

 

TM

95.51 ± 3.34

93.48 ± 2.94

91.70 ± 3.05

96.03 ± 1.23

0.54

PM

47.58 ± 4.19

44.38 ± 2.15

49.34 ± 2.29

50.58 ± 2.87

6.31

VCL

75.74 ± 8.59

77.03 ± 5.68

92.29 ± 5.45

79.66 ± 5.59

5.18

VAP

39.36 ± 3.88

38.35 ± 2.68

48.24 ± 2.49

41.71 ± 3.08

5.97

VSL

26.74 ± 2.72

25.5 ± 2.02

34.45 ± 1.80

28.81 ± 2.55

7.74

STR

67.95 ± 1.75

66.25 ± 1.23

71.43 ± 0.94

68.52 ± 1.55

0.84

LIN

36.26 ± 1.97

33.07 ± 0.64

37.62 ± 1.83

35.93 ± 1.64

-0.91

WOB

53.21 ± 2.05

49.92 ± 0.51

52.56 ± 1.96

52.31 ± 1.41

-1.69

ALH

3.82 ± 0.37

4.02 ± 0.22

4.37 ± 0.21

4.09 ± 0.18

7.07

BCF

4.12 ± 0.55

4.13 ± 0.28

3.11 ± 0.21

4.25 ± 0.25

3.16

MAD

68.80 ± 7.44

70.82 ± 4.77

69.35 ± 6.00

72.31 ± 3.46

5.10

  1. abc Different superscript letters indicate significant different (P < 0.05) in each row
  2. ALH = Amplitude of Lateral Head Displacement (µm), BCF = Beat Cross Frequency (Hz), HOS = Hypo Osmotic Swelling, LIN = Linearity (%), MAD = Mean Angular Displacement (°), STR = Straightness (%), VAP = Velocity Average Path (µm/s), VCL = Velocity Curvilinear (µm/s), VSL = Velocity Straight Path (µm/s), and WOB = Wobble (%)