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Table 3 Top 20 differentially common over-represented WCL proteins vs. healthy control in the carcinoma cell lines

From: Proteomic analysis of extracellular vesicles derived from canine mammary tumour cell lines identifies protein signatures specific for disease state

Common over-represented proteins

Accession number

Protein name

Protein abbreviation

MTH52C

Log2FC

1305

Log2FC

DT1406TB

Log2FC

A0A8I3MKP5

Serpin B5

SERPINB5

5.987

11.184

4.273

A0A8I3RRG1

Heat shock protein family B (small) member 6

HSPB6

6.269

9.503

4.919

A0A8I3Q497

RAB8A, member RAS onco family

TPM4

7.749

8.158

1.989

A0A8P0P7T7

Transforming acidic coiled-coil containing protein 1

TACC1

6.187

6.939

4.416

A0A8I3N4I3

Trophoblast glycoprotein

TPBG

4.280

5.255

7.631

A0A8I3Q6P3

RAB8A, member RAS onco family

TPM4

7.882

6.517

2.211

A0A8I3P542

fatty acid amide hydrolase

FAAH

3.651

7.188

5.457

A0A8I3S7B1

Bridging integrator 1

BIN1

5.290

6.640

3.024

A0A8I3PMV7

CutA divalent cation tolerance homolog

CUTA

5.372

7.128

2.272

A0A8P0NGG9

Galectin

LGALS3

1.521

7.307

5.419

A0A8I3NMV9

PBX homeobox interacting protein 1

PBXIP1

4.881

5.810

3.389

A0A8I3MUR7

DAB adaptor protein 2

DAB2

4.991

5.599

3.370

A0A8I3RR31

Myosin regulatory light chain 12B

MYL12B

2.191

6.458

5.301

A0A8I3NML2

Clathrin light chain

CLTB

3.828

7.208

2.910

A0A8I3MJ17

Abl interactor 1

ABI1

5.757

6.161

1.656

A0A8I3NZF1

Acylphosphatase

ACYP1

3.241

6.659

3.557

A0A8P0SCK9

IF rod domain-containing protein

KRT86

3.257

4.057

5.955

A0A8P0N5R9

Glycoprotein nmb

GPNMB

1.419

7.333

4.212

A0A8P0P6 × 6

Cadherin-2

CDH2

1.605

5.693

5.647

A0A8I3P9R4

Ectonucleoside triphosphate diphosphohydrolase 3

ENTPD3

3.408

5.338

4.067

Common under-represented proteins

Accession number

Protein name

Protein abbreviation

MTH52C

Log2FC

1305

Log2FC

DT1406TB

Log2FC

A0A8I3PDZ7

RNA-splicing ligase RtcB homolog

RTCB

-6.061

-5.268

-6.013

A0A8I3P3E3

Transglutaminase 3

TGM3

-4.386

-3.891

-6.058

A0A8I3PJ19

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

SMARCA4

-4.700

-5.013

-4.087

A0A8I3MM38

Fibrillarin

FBL

-4.018

-7.114

-1.962

A0A8I3RZK8

Zinc finger CCHC-type containing 3

ZCCHC3

-3.665

-5.718

-3.381

A0A8P0STD7

40 S ribosomal protein S2

3 SV

-5.069

-5.791

-0.657

A0A8I3PKM8

Nuclear transcription factor, X-box binding 1

NFX1

-3.588

-4.875

-3.002

A0A8I3Q3M7

Cell division cycle 45

CDC45

-1.025

-7.065

-2.788

A0A8I3PMM3

Cellular tumor antigen p53

TP53

-2.145

-3.902

-4.705

A0A8I3N527

Nuclear RNA export factor 1

NXF1

-3.800

-5.267

-1.536

A0A8I3PYF0

FACT complex subunit

SUPT16H

-3.071

-5.592

-1.828

A0A8P0SQL8

Ribosomal protein L37a

3 SV

-3.965

-5.827

-0.663

A0A8I3MSY1

Nucleosome assembly protein 1 like 1

NAP1L1

-1.885

-4.066

-4.485

A0A8P0T777

WD repeat domain 70

WDR70

-2.919

-6.089

-1.424

A0A8I3NZ09

Transducin beta like 3

TBL3

-1.844

-3.417

-4.811

A0A8P0N906

DNA polymerase epsilon catalytic subunit

POLE

-2.923

-3.493

-3.655

A0A8I3P419

Serine/threonine-protein kinase PRP4 homolog

PRPF4B

-4.051

-3.781

-2.207

A0A8I3S988

Chromosome transmission fidelity factor 18

CHTF18

-1.533

-6.296

-2.166

A0A8I3MIZ2

Pumilio RNA binding family member 3

PUM3

-3.700

-3.651

-2.437

A0A8I3PVA9

CWC22 spliceosome associated protein homolog

CWC22

-3.135

-4.297

-2.187