Table 4 Top 10 differentially over- and under-represented proteins identified in adenoma EVs vs. healthy control

Accession number

Protein

Log2FC

Adj. P-value

A0A8I3QAX6

CTPS2

8.361

1.17E-04

A0A8I3NTB5

CANT1

8.065

1.12E-04

A0A8I3PAV5

TCN2

7.800

2.25E-03

A0A8I3P342

ISG15

7.219

1.16E-03

A0A8I3MLA0

MFAP2

6.528

1.10E-03

A0A8P0TVC6

ADAP1

6.482

1.24E-03

A0A8I3PFH2

ZPLD1

6.409

2.46E-05

J9NVI2

BST2

6.396

5.88E-03

A0A8I3MKR1

IFI44

6.365

1.49E-03

A0A8P0N757

PRSS23

6.058

2.00E-04

Under-represented proteins

Accession number

Protein

Log2FC

Adj. P-value

A0A8I3PNQ7

MXRA8

-8.773

4.98E-04

A0A8I3N7R9

ANGPTL2

-8.497

1.65E-04

A0A8I3Q6P3

TPM4

-7.629

4.39E-03

A0A8I3NDQ9

TNN

-7.596

3.69E-04

A0A8I3Q497

TPM4

-7.441

4.26E-03

A0A8I3PGJ4

PTX3

-7.425

1.51E-03

A0A8I3MER3

NN*

-7.400

2.04E-03

A0A8I3NUH5

NDUFB8

-7.308

4.40E-04

A0A8P0T552

RBP4

-7.285

2.86E-02

A0A8P0S626

SERPINB8

-7.266

1.40E-04