Skip to main content
Fig. 1 | BMC Veterinary Research

Fig. 1

From: Overexpression of IL-6 and STAT3 may provide new insights into ovine pulmonary adenocarcinoma development

Fig. 1

(a-f). Hematoxylin and eosin and immunohistochemistry for IL-6 and STAT3. a. Normal lung tissue, control group, case 2. b. Pulmonary adenocarcinoma, acinar type, OPA group, case 3. The tumor is composed of cubical to polygonal cells arranged in variably sized and irregular acini (arrow), associated with moderate fibrovascular stroma. c. Normal lung tissue, control group, case 2. IL-6 immunoexpression was observed in rare type I and type II (arrow) pneumocytes with low intensity. d. Pulmonary adenocarcinoma, acinar type, OPA group, case 3. There is strong immunolabeling for IL-6 in the cytoplasm of almost all neoplastic epithelial cells (arrows). e. Normal lung tissue, control group, case 2. Mild immunolabeling for STAT3 in the cytoplasm of scattered type II pneumocytes cells is present (arrow). f. Pulmonary adenocarcinoma, acinar type, OPA group, case 1. There is strong immunolabeling for STAT3 in the cytoplasm of almost all neoplastic epithelial cells. Nuclear immunoreactivity (arrow) is also present in some areas of tumors (inset)

Back to article page

BMC Veterinary Research

ISSN: 1746-6148

Contact us