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Table 3 Effects of boar and SINS on average fold-expression of selected genes in qPCR

From: Screening for transcriptomic associations with Swine Inflammation and Necrosis Syndrome

Gene

 

Total

DU

PI+

PI-

SINS-high

SINS-low

PBoar

PSINS

R2Boar

R2SINS

GYPA

Mean

2.06

1.89

1.98

2.31

0.62

3.50

n.s.

0.029

0.40%

27.80%

 

SE

0.60

0.98

1.10

1.03

0.86

0.83

    

VEGFA

Mean

1.26

1.32

1.12

1.33

1.70

0.81

n.s.

0.008

1.50%

35%

 

SE

0.15

0.24

0.27

0.25

0.21

0.20

    

CCL2

Mean

1.52

1.61

1.90

1.03

0.94

2.10

n.s.

0.029

5.30%

13.90%

 

SE

0.33

0.54

0.61

0.57

0.485

0.46

    

CRP

Mean

1.59

1.66

1.29

1.81

2.25

0.93

n.s.

0.060

1%

10%

 

SE

0.49

0.81

0.91

0.85

0.71

0.69

    

IGSF5

Mean

4.16

0.91

3.24

8.34

6.20

2.13

n.s.

n.s.

15.90%

6.60%

 

SE

1.70

3.01

3.01

2.81

2.35

2.46

    

S100A12

Mean

1.52

1.59

1.03

1.57

0.76

2.03

n.s.

0.030

0%

22.10%

 

SE

0.36

1.43

0.60

1.84

0.35

1.68

    

TMEM52B

Mean

2.97

2.28

3.08

3.56

5.04

1.79

n.s.

0.043

3.10%

34.97%

 

SE

0.67

1.05

1.31

1.10

0.97

1.09

    
  1. SINS-high: Piglets with highest SINS-scores (z-scores between − 13.86 and − 5.39); SINS-low: piglets with lowest SINS-scores (z-scores between 4.18 and 12.83). P: significance; DU: offspring of the Duroc boar; PI-: offspring of the unfavourable Pietrain boar; PI+: offspring of the favourable Pietrain boar; SE: Standard error. R2: Coefficient of determination. Fold-changes are based on delogarithmised data