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Table 2 The MIC values for quinolone, fluoroquinolone, and tetracycline antibiotics of F. oreochromis, F. covae, and F. davisii isolated from diseased farmed freshwater fish in Thailand

From: Comparative genomic analysis of Flavobacterium species causing columnaris disease of freshwater fish in Thailand: insights into virulence and resistance mechanisms

Species

Isolates no

MIC value (μg/ml)

OA

 

ENR

 

OT

 

F. oreochromis

KCRT1906a

0.25

WT

0.015

WT

0.125

WT

F. oreochromis

RCBRT1901a

 > 4

NWT

0.125

NWT

0.125

WT

F. oreochromis

SKNRT2101a

0.25

WT

0.015

WT

0.125

WT

F. oreochromis

GR2101

 > 4

NWT

 > 1

NWT

0.06

WT

F. oreochromis

CNRT2201a

 > 4

NWT

 > 1

NWT

0.125

WT

F. oreochromis

UBRT2201a

0.25

WT

0.015

WT

0.125

WT

F. oreochromis

KCRT2301a

 > 4

NWT

 > 1

NWT

0.06

WT

F. oreochromis

KCRT2304a

0.25

WT

0.015

WT

0.125

WT

F. oreochromis

SRBRT2303

0.25

WT

0.015

WT

0.125

WT

F. covae

PCBSB2203a

 > 4

NWT

 > 1

NWT

 > 16

NWT

F. covae

PCBSB2201

1

NWT

 > 1

NWT

0.125

WT

F. davisii

KCRT2007a

0.25

WT

0.06

NWT

0.125

WT

  1. OA oxolinic acid, ENR enrofloxacin, OT tetracycline, WT Wild-type, NWT Non-wild-type. Wild-type and non-wild-type isolates determination based on the epidemiological cut-off values (ECVs) for OA, ENR, OT from the previous study [30]
  2. aGenomes sequenced in the present study