Fig. 3
From: Participation of COX2/mPGES1/PGE2 in mouse and human endometrial stromal decidualization
Expression and function of prostaglandin synthases during human in vitro decidualization. (A)mPGES1 expression. (B)cPGES expression. (C)mPGES2 expression. (D) Effects of MK886 on human in vitro decidualization. (E) Effects of Valdecoxib on human in vitro decidualization. Human endometrium stromal cells were induced for in vitro decidualization by MPA and db-cAMP for 6 days. Cells were treated with DMSO as the control. IGFBP1 expression was significantly inhibited by 5 and 10 μM of MK886 or Valdecoxib, respectively(n = 3). Data were normalized with RPL7. *P < 0.05