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Table 5 Oncology CROM: content analysis

From: A rapid state-of the-art review of client-reported outcomes measures used to assess dogs’ clinical signs and quality of life during chemotherapy

VCOG-CTAE category or QoL domain

Mellanby et al.,2003

Bowles et al., 2010

Rau et al., 2010

Lynch et al., 2011

Hamilton et al., 2012

Iliopoulou et al., 2013 (

Bianchi et al., 2021

Fournier et al., 2021

Jugan et al., 2021

Matsuyama et al., 2021

N studies

VCOG clinical signs

          

Gastrointestinal

Appetite changes (increase and decrease)

 

9

Measure of food intake

      

   

1

Chewing or

swallowing

       

 

2

Nausea

  

     

 

2

Vomiting

 

 

 

7

Defaecation

(Diarrhoea and/or)

 

 

 

7

Constipation

      

 

3

Weight changes

       

 

2

Renal/urological

Hydration/

urination

   

  

 

4

Pulmonary/ respiratory

Breathing

      

  

2

Coughing

      

  

2

Pain

Owners’ perception of pain

   

 

  

4

Dermatological/skin

Rashes, itching

        

 

1

New lumps/discharge

 

     

  

2

Other clinical signs of health related QoL

Lethargy/rest/sleep

 

 

   

  

3

Mobility/ambulatory activity (increase/decrease)

  

 

7

Hygiene (cleanliness/coat condition)

   

  

   

2

Subjective QoL and wellbeing

Specific item(s) indicative of dogs mental/social QoL or wellbeing

         

1

Happiness/joy/enjoyment

   

 

  

4

Mental status/mood (incl. anxiety)

   

 

  

4

Interaction/play

     

 

  

2

Item of global rating of QoL or general health

 

 

  

6

Other subjective views

Client views on CT/relationship with pet etc.

   

 

  

4

N category or domain totals

3

7

5

9

4

8

14

17

9

5