An extensively hydrolysed protein-based extruded diet in the treatment of dogs with chronic enteropathy and at least one previous diet-trial failure: a pilot uncontrolled open-label study

Table 4 Haematological variables and biochemical analytes outside of the laboratory reference interval in dogs with confirmed chronic enteropathy

Variable	Screening visit (n = 13)		Visit 2 (n = 12) ^a		Visit 3 (n = 11)
Variable	Above	Below	Above	Below	Above	Below
Erythrocyte count	1	0	1	0	1	0
Haemoglobin	1	0	0	1	2	1
Haematocrit	5	0	4	0	4	0
MCHC	1	0	1	0	0	0
MCH	2	1	1	2	0	3
MCV	7	0	5	0	7	0
White blood cell count ^b	0	2	2	1	0	1
Neutrophil count ^b	0	1	1	1	0	1
Eosinophil count ^b	0	1	1	2	0	1
Basophil count ^b	0	0	1	0	0	0
Lymphocyte count ^b	0	0	2	0	0	0
Monocyte count ^b	0	1	1	0	0	0
Platelet count	0	3	0	1	0	0
Urea	2	1	0	1	0	0
Creatinine	0	0	0	0	0	1
Gamma-glutamyl transferase	0	0	1	0	1	0
Aspartate aminotransferase	1	0	1	0	1	2
Alanine aminotransferase	2	0	0	0	1	0
Alkaline phosphatase	3	0	2	0	1	0
Glucose ^c	3	0	4	0	4	1
Total protein	0	9	0	8	0	2
Albumin	0	10	0	9	0	6
Total bilirubin	0	0	1	0	0	0
Calcium	0	3	0	2	0	3
Phosphate	0	1	2	3	2	0
Cholesterol	1	1	2	0	3	0

All results represent the number of dogs with a result either above or below the reference interval of the respective laboratory. For full details, please see Additional File 1. Please note that blood samples were not taken at visit 1. ^a One of the 13 dogs in the study did not have haematology or biochemistry data at this timepoint (visit 2), as a result of being withdrawn due to administration of prednisolone for a neurological condition. ^b White blood cell counts were not available in one dog at visit 3 due to degeneration of the samples. ^c It was not possible to determine the glucose concentration for one and two dogs at visits 0 and 3, respectively, because the blood samples were not appropriately handled. MCHC: Mean corpuscular haemoglobin concentration; MCH: Mean corpuscular haemoglobin; MCV: Mean corpuscular volume

ISSN: 1746-6148