Table 1 Number of studies included in the meta-analysis, proportion of resistant Enterobacterales isolates (%), 95% Confidence Interval (CI), and I² values for each antimicrobial class

Amphenicols

85

2

1–4

92.4

Amynoglicosides

97

10

8–14

96.9

Beta lactam—beta lactamase inhibitor

61

9

5–13

97.4

Carbapenems

44

3

1–7

95.7

Carboxypenicillin

5

5

2–10

68.8

First/Second generation cephalosporins

68

8

4–12

98.2

Fluoroquinolones

81

3

2–5

94.5

Lincosamides

8

5

1–11

89.9

Macrolides^a

14

27

12–44

98.6

Monobactams

13

9

2–18

92.6

Nitrofurans

11

0

0–2

46.5

Penicillins

94

18

13–23

98.2

Polymyxins

21

1

0–2

75

Quinolones

68

5

3–8

95.9

Sulphonamides

36

12

6–20

98

Tetracyclines

95

14

10–17

97

Third/Fourth/Fifth generation cephalosporins

81

5

3–7

95.1

Trimethoprim—sulfonamide combinations

79

7

4–9

94.6

ARGs

47

26

19–33

98.4

MDR

92

7

5–10

95.3

CIAs

104

23

18–28

98.3