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Table 1 Relative amounts of monomers and high molecular weight (HMW) species of B-T0, BBAC-T0, B-T4 and BBAC-T4

From: Preserved bevacizumab (Avastin®) eye drops for application in multidose containers – an in-vitro characterisation

Sample

Monomers (%)

HMW (%)

MW monomer (kDa)

B-T0

97.57 ± 0.02

2.59 ± 0.02

152.15 ± 0.19

BBAC-T0

97.35 ± 0.22

2.65 ± 0.22

151.68 ± 0.37

B-T4

97.27 ± 0.01

2.73 ± 0.01

152.06 ± 0.13

BBAC-T4

97.25 ± 0.26

2.75 ± 0.26

152.41 ± 0.55

  1. Values represent means (n = 3) ± SD. Monomers (%) = Main peak area/total peak area × 100; HMW (%) = HMW peak area/total peak area × 100. MW monomer = molecular weight in kDa
  2. HMW high molecular weight species
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BMC Veterinary Research

ISSN: 1746-6148

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