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Table 3 RBCs Hemolyzed concentration of CAT, SOD & GPx in four different groups. Data are expressed as median (25–75%)

From: The protective role of melatonin and agomelatine against oxidative stress following laparoscopic ovariectomy in dogs

 

Factor

Groups (n = 6)

Day − 1

Day 0

Day 3

Day 8

P value

 

CAT (nmol/g Hb)

C

5.5 (5.12–5.87)

6.2 (5.62–7.45)

4.6 (4.22–5.82)

5.3 (5.2–5.47)

0.06

LO

5.25 (4.60–6.77)

6 (6.00-7.3)

6 (4.6–7.30)

6 (5.20–6.77)

0.60

ALO

4 (3.50–5.10)

4.8 (4.22–5.45)

4.35 (3.15–5.55)

4.7 (4.30–5.45)

0.46

MLO

3.6 (3.27–4.3)

4.3 (3.57–5.22)

4.85 (3.45–6.12)

3.6 (3.22–4.4)

0.24

P value

 

**

0.21

0.42

0.24

 
 

SOD

(U/g Hb)

C

475 (431.25–506.50)

383.5 (309–434)

a422.5 (361.5-561.5)

470 (384.5-535.75)

0.42

LO

408 (390.75-451.25)

373.5 (328.5-516.5)

a406.5 (370.25–455)

466 (379.5-554.25)

0.49

ALO

487.5 (433.25-543.25)

496.5 (443.25–644)

b608.5 (557.5-665.75)

598 (553.75–622)

0.36

MLO

556 (475-580.25)

515 (470.75-601.25)

ab470.5 (399.75–611.50)

543 (517.50-574.25)

0.33

P value

 

**

0.14

0.009*

0.11

 
 

GPx (mU/g Hb)

C

247 (240.25-254.75)

303 (289.5-343.5)

281 (218.5–316)

a270 (235–303)

0.10

LO

316 (247.5-365.75)

278 (259–341)

286.5 (241.75–341)

a267.5 (251.75-284.25)

0.53

ALO

317 (307.75-342.25)

300.5 (261.25–340)

331.5 (306-367.75)

b328.5 (296.25–366)

0.45

MLO

311.5 (286.5-332.75)

303 (290-328.25)

323.5 (289.5-351.25)

b338.5 (312.5–374)

0.06

P value

 

**

0.53

0.44

0.003*

 
  1. ab In each column, different superscript letters on the left side of the median indicate significant differences between groups (p < 0.05)
  2. ab In each row, different superscript letters on the right side of the median indicate significant differences between sampling days (p < 0.05)
  3. * The right P value column indicates significant differences between sampling days (p < 0.05)
  4. * The P value indicates significant differences between groups (p < 0.05) in each row
  5. ** According to the Quade Non-Parametric test, the effect of day − 1 in the study between groups has been adjusted
  6. Abbreviations: C = Control, LO = Laparoscopic Ovariectomy, ALO = Agomelatine + Laparoscopic Ovariectomy, MLO = Melatonin + Laparoscopic Ovariectomy