Fig. 5

Histomorphometric analysis of the newly formed tissue in vivo. (A) The epithelial gap between the two wound edges as well as (B) the count of inflammatory cells at the wound site were quantified using ImageJ. (C) The number of new blood vessels was quantified in 5 images per section. (D) The size of the new blood vessels was assessed with ImageJ. Groups marked with different letters represent statistically significant differences (p < 0.05), whereas groups sharing the same letter show no significant difference. Differences were evaluated using one-way ANOVA followed by Tukey’s HSD post hoc test