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Table 2 Haematological and haemogram-derived inflammatory markers in healthy cats and FIP cats before and after treatment

From: Evaluation of selected inflammatory markers in cats with feline infectious peritonitis before and after therapy

Parameter

HEALTHY cats

FIP cats

  

Before treatment

pa

After treatment

pb

WBC (× 109/L)

n = 28

8.80; 7.65–12.68

n = 36

14.57; 9.07–20.76

0.006

n = 30

10.60; 8.93–12.10

0.225

RBCc (× 1012/L)

n = 28

9.38 ± 1.56

n = 36

7.15 ± 1.90

 < 0.001

n = 30

9.94 ± 1.16

0.065

HCTc

(L/L)

n = 28

0.413 ± 0.059

n = 35

0.279 ± 0.067

 < 0.001

n = 30

0.394 ± 0.051

0.131

HGBc

(g/L)

n = 28

127.6 ± 16.1

n = 36

91.9 ± 22.3

 < 0.001

n = 30

131.2 ± 14.0

0.362

NEUT

(× 109/L)

n = 28

4.58; 2.74–7.23

n = 36

12.03; 8.26–18.17

 < 0.001

n = 30

4.83; 4.17–6.05

0.560

LYMPH

(× 109/L)

n = 28

3.24; 2.68–4.26

n = 36

1.55; 1.05–2.74

 < 0.001

n = 30

3.98; 2.91–6.09

0.102

MONO

(× 109/L)

n = 28

0.290; 0.190–0.608

n = 36

0.390; 0.150–0.680

0.839

n = 30

0.210; 0.130–0.308

0.072

PLT

(× 109/L)

n = 28

263; 221–333

n = 27

258; 168–346

0.613

n = 29

407; 287–435

0.002

NLR

n = 28

1.47; 0.82–2.45

n = 36

7.43; 3.95–11.13

 < 0.001

n = 30

1.16; 0.78–1.58

0.234

LMR

n = 28

10.50; 6.41–15.95

n = 34

6.01; 1.71–12.70

0.014

n = 29

18.50; 14.09–26.93

0.001

PLR

n = 28

74.9; 57.8–128.6

n = 27

156.3; 94.2–238.5

0.007

n = 29

88.0; 62.1–126.9

0.737

SII (× 109/L)

n = 28

444.5; 185.4–652.4

n = 27

2265.7; 869.3–3158.4

 < 0.001

n = 29

431.5; 264.2–722.6

0.503

  1. IQR (25 th to 75 th percentile); WBC white blood cell count; RBC red blood cell count; HGB haemoglobin concentration; HCT haematocrit; NEUT neutrophil concentration; LYMPH lymphocyte concentration; MONO monocyte concentration; PLT platelet concentration; NLR neutrophil-to-lymphocyte ratio; LMR lymphocyte-to-monocyte ratio; PLR platelet-to-lymphocyte ratio; SII systemic immune-inflammatory index; n number of data included in the statistical analysis
  2. acontrol vs FIP before treatment, significant difference, p < 0.05 (bold)
  3. bcontrol vs FIP after treatment, significant difference, p < 0.05 (bold)
  4. cvalues reported as mean ± standard deviation, other parameters are reported as median