Table 1 Accuracy (bias), repeatability (CV) and total imprecision (CV) data at the different QC levels for iohexol and creatinine-d3 in VAMS samples (n = 2 × 3) calculated via One-way ANOVA
Nominal value (µg/mL) | Accuracy (bias) | Repeatability (CV) | Total imprecision (CV) | ||
|---|---|---|---|---|---|
Iohexol | LLOQ | 2 | 1.4% | 8.0% | 8.0% |
QCL | 5 | -2.9% | 9.4% | 9.4% | |
QCM | 50 | -5.4% | 0.9% | 7.8% | |
QCH | 300 | -0.5% | 4.2% | 7.2% | |
QCL cat | 5 | 1.0% | 5.5% | 7.5% | |
QCH cat | 300 | 2.5% | 5.3% | 7.2% | |
Creatinine-d3 | LLOQ | 2 | -2.2% | 8.3% | 8.3% |
QCL | 5 | -3.3% | 9.6% | 9.6% | |
QCM | 50 | -2.6% | 2.5% | 3.0% | |
QCH | 300 | 0.9% | 2.8% | 6.6% | |
QCL cat | 5 | 1.1% | 5.5% | 8.0% | |
QCH cat | 300 | 2.8% | 4.3% | 6.2% |