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Table 3 Association of clinicopathological parameters and MCL-1 expression

From: Overexpression of MCL-1 in canine hepatocellular carcinoma and its efficacy as a prognostic marker

 

Number of

tissues

MCL-1 expression

P-value

Low

High

Hepatocellular carcinoma

    

Median age (range)

30

11 (9–13)

13 (6–17)

P = 0.197

Subtypes

   

P = 0.276

 Massive

25

9

16

 Nodular

4

0

4

 Diffuse

1

0

1

Tumor location

   

P = 0.146

 Left

16

7

9

 Central

9

2

7

 Right

5

0

5

Size of tumor

   

P = 0.046*

 ≤ 5 cm

9

5

4

 > 5 cm

21

4

17

Blood analysis

   

P = 0.109

 ALT

   

 Normal

5

3

2

 High

25

6

19

AST

   

P = 0.936

 Normal

17

5

12

 High

13

4

9

ALP

   

P = 0.120

 Normal

1

1

0

 High

29

8

21

GGT

   

P = 0.690

 Normal

15

5

10

 High

15

4

11

Metastasis

   

P = 0.034*

 Yes

12

1

11

 No

18

8

10

Hepatic disease

    

 Vacuolar hepatopathy

11

10

1

P = 0.200

 Inflammation

17

11

6

 Others

2

2

0

  1. *Chi-square test indicating significant relevance of high MCL-1 immunostaining and clinicopathological parameters (P < 0.05)