From: Overexpression of MCL-1 in canine hepatocellular carcinoma and its efficacy as a prognostic marker
Number of tissues | MCL-1 expression | P-value | ||
---|---|---|---|---|
Low | High | |||
Hepatocellular carcinoma | ||||
Median age (range) | 30 | 11 (9–13) | 13 (6–17) | P = 0.197 |
Subtypes | P = 0.276 | |||
Massive | 25 | 9 | 16 | |
Nodular | 4 | 0 | 4 | |
Diffuse | 1 | 0 | 1 | |
Tumor location | P = 0.146 | |||
Left | 16 | 7 | 9 | |
Central | 9 | 2 | 7 | |
Right | 5 | 0 | 5 | |
Size of tumor | P = 0.046* | |||
≤ 5 cm | 9 | 5 | 4 | |
> 5 cm | 21 | 4 | 17 | |
Blood analysis | P = 0.109 | |||
ALT | ||||
Normal | 5 | 3 | 2 | |
High | 25 | 6 | 19 | |
AST | P = 0.936 | |||
Normal | 17 | 5 | 12 | |
High | 13 | 4 | 9 | |
ALP | P = 0.120 | |||
Normal | 1 | 1 | 0 | |
High | 29 | 8 | 21 | |
GGT | P = 0.690 | |||
Normal | 15 | 5 | 10 | |
High | 15 | 4 | 11 | |
Metastasis | P = 0.034* | |||
Yes | 12 | 1 | 11 | |
No | 18 | 8 | 10 | |
Hepatic disease | ||||
Vacuolar hepatopathy | 11 | 10 | 1 | P = 0.200 |
Inflammation | 17 | 11 | 6 | |
Others | 2 | 2 | 0 |