Fig. 3

Bland–Altman plots comparing interstitial glucose values measured by remote RT-CGMS (before and after calibration) with reference blood glucose values obtained using PBGM (Accu-Chek). (a) Differences prior to calibration. (b) Differences following calibration. Each point represents a paired glucose measurement (n = 46). Different colors correspond to different RT-CGMS sensors used during the study. The central solid black line indicates the mean bias, while the dashed black lines represent ISO 15197:2013 accuracy limits: ±0.83 mmol/L for glucose concentrations below 5.5 mmol/L and ± 15% for concentrations at or above 5.5 mmol/L. Percentages represent the proportion of samples falling within these limits (central % value). PBGM, portable blood glucose meters; RT-CGMS, real-time continuous glucose monitoring